Fig. 1
From: Proteome-wide mendelian randomization study implicates therapeutic targets in common cancers
Workflow of Mendelian randomization study revealing causality from plasma protein on site-specific cancers. PPI: protein–protein interaction; PCa: prostate cancer; BRCa: breast cancer; LCa: lung cancer; CCa: colorectal cancer; BLCa: bladder cancer; OCa: ovarian cancer; KCa: kidney cancer; GCa: gastric cancer; cis-pQTL: cis-protein quantitative trait loci; PPH4: posterior probability of hypothesis 4