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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: DNA methylation regulator-mediated modification patterns and risk of intracranial aneurysm: a multi-omics and epigenome-wide association study integrating machine learning, Mendelian randomization, eQTL and mQTL data

Fig. 3

Consensus clustering results in IA cohorts. A Consensus clustering matrix of k = 2 as the optimal cluster number. B CDF curves of the consensus score from k = 2–9. C PCA principal component analysis of two clusters. Each subgroup was distinguished by different colors. Heat map (D) and box plot (E) showing 19 MRGs differentially expressed in A and B cluster. *p < 0.05; **p < 0.01; ***p < 0.001; ns no statistical significance

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Journal of Translational Medicine

ISSN: 1479-5876

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