Fig. 1From: DNA methylation regulator-mediated modification patterns and risk of intracranial aneurysm: a multi-omics and epigenome-wide association study integrating machine learning, Mendelian randomization, eQTL and mQTL dataGenetic variations and expression of MRGs in IA tissue samples. A Localization of 19 MRGs on the 23 chromosome. B PPI analysis of 19 MRGs. C At the tissue level, principal component analysis separates normal (grey), RIA (yellow) and UIA samples (blue). Heat map (D) and box plot (E) showing 19 MRGs differentially expressed in normal, RIA and UIA tissues. *p < 0.05; **p < 0.01; ***p < 0.001; ns no statistical significanceBack to article page