| Â | Primary analysis | Sensitivity analysis |
|---|
Model 1 | Model 2 | Model 3 |
|---|
HDL-C | 0.50(0.46–0.54) | 0.68(0.61–0.75) | 0.76(0.60–0.95) | 0.78(0.62–0.99) |
LDL-C | 0.90(0.87–0.93) | 0.97(0.94–1.01) | 0.99(0.77–1.26) | 1.01(0.79–1.29) |
TC | 0.89(0.87–0.92) | 0.97(0.94–1.00) | 0.98(0.79–1.21) | 0.97(0.78–1.20) |
TG | 1.13(1.11–1.16) | 1.10(1.06–1.13) | 1.08(1.02–1.13) | 1.07(1.02–1.13) |
- Hazard ratios (HRs) are provided with 95% confidence intervals
- Model 1: adjusted for age, sex, region, BMI, hypertension, diabetes mellitus, the top 10 genetic principal components
- Model 2: model1 + income, Townsend deprivation index, smoking, drinking, physical activity (IPAQ), sleep duration, antihypertensive medications usage at baseline and during follow-up, hypoglycemic medications usage at baseline and during follow-up
- Model 3: model1 + income, Townsend deprivation index, smoking, drinking, physical activity (IPAQ), sleep duration, antihypertensive medications usage at baseline and during follow-up, hypoglycemic medications usage at baseline and during follow-up, HDL-C, LDL-C, TC, and TG
- HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides, IPAQ international physical activity questionnaire, BMI body mass index, HR hazard ratio
