Fig. 5
From: Hypoxia-induced AFAP1L1 regulates pathological neovascularization via the YAP-DLL4-NOTCH axis
AFAP1L1-related gene enrichment analysis. A STRING protein network map of top 100 AFAP1L1-related genes from the GEPIA2 database. B GO analysis based on the top 100 AFAP1L1-related genes. C According to the differentially expressed genes between the high and low expression groups of AFAP1L1, GSEA analysis revealed the top 25 up-regulated and the top 25 down-regulated enrichment biological processes. Enrichment biological processes ranked based on the normalized enrichment scores (NES) are shown in the heat map. D Average correlations between AFAP1L1 and 14 functional states in different cancers from the CancerSEA database and the bar charts show the number of datasets in which AFAP1L1 is significantly related to the corresponding state