Fig. 3

Diagnostic performance of mNGS-CNV analysis. A A representative chromosome copy number plot of an MPE patient with both copy number gain and loss events. B A contingency table shows the mNGS-CNV modeling results compared to clinical pathological diagnosis. C The sensitivity, specificity, and accuracy of mNGS-CNV prediction based on B are shown by the bar plot. D The Receiver Operating Characteristic (ROC) curve shows the performance of mNGS-CNV LOOCV result with an area under the curve (AUC) of 0.851