Table 3 Summary of epilepsy seizure burden and responder rates for 100% and 50% PER groups
100% adherent (~ 10 mg/kg/day) N = 10 | 50% adherent (~ 5 mg/kg/day) N = 12 | |
|---|---|---|
Avg seizure frequency (# per day) | ||
Baseline | 0.871 ± 1.115 | 0.747 ± 0.981 |
Treatment | 0.246 ± 0.303 | 1.262 ± 1.352 |
Median Δ [95% CI] | − 50% [− 100, 51] | + 54%* [− 43, 187] |
> 25% responder rate #/n | 5/10 | 5/12 |
> 50% responder rate #/n | 5/10** | 0/12 |
Seizure freedom #/n | 3/10 | 0/12 |