Fig. 7

Hyperoside treatment counteracts light-induced alterations in the retinal gene expression. A PCA of RNA-seq data. B Correlation heatmap of DEGs. R, the Kendall correlation coefficient. C Heat map generated from hierarchical clustering analysis of the DEGs. D GSEA enrichment scatter plot (LE vs NLE). E GSEA enrichment scatter plot (HYP vs LE). NES normalized enrichment score, HYP the light-exposed mice treated with 50 mg/kg hyperoside, LE the light-exposed mice treated with vehicle, NLE the vehicle-treated mice without light exposure