Fig. 3

Hyperoside protects against light-induced photoreceptor morphological degeneration. A Representative OCT scans from the superior retinas. B The ONL thickness measured at 250, 500, 750 and 1000 μm from ONH in the inferior and superior retinas. Data were expressed as mean ± SEM (n = 6 per group). ***Compared to NLE, P < 0.001; ^##compared to LE, P < 0.01, ^###compared to LE, P < 0.001; ns, not significant. HYP-L the light-exposed mice treated with 12.5 mg/kg hyperoside, HYP-M the light-exposed mice treated with 50 mg/kg hyperoside, HYP-H the light-exposed mice treated with 200 mg/kg hyperoside, INL inner nuclear layer, IS inner segment, LE the light-exposed mice treated with vehicle, NLE the vehicle-treated mice without light exposure, ONH optic nerve head, ONL outer nuclear layer, OPL outer plexiform layer, OS outer segment, RPE retinal pigment epithelium