Fig. 1

Hyperoside inhibits SNP-induced photoreceptor cell death. 661W cells pretreated with vehicle or hyperoside at the indicated concentrations were incubated in the presence or absence of 300 μM SNP for 4 h. A YOYO-1 positivity (in green) recorded by Incucyte live cell analysis platform 10 h after the termination of SNP stimulation. Scale bar, 300 μm. B Quantification of YOYO-1 confluence at 1-h intervals using Incucyte Live-Cell Analysis System. Data were expressed as mean ± SEM. (n = 6 per group). ***Compared to VC, P < 0.001; ^###compared to SNP, P < 0.001. VC, the vehicle-treated cells without SNP exposure; SNP, the SNP-stimulated vehicle-treated cells; HYP, the SNP-stimulated cells treated with hyperoside