Fig. 4
Acute systemic inflammatory reaction and diet during Metformin administration. A Blood systemic metabolic and inflammatory markers from baseline (day 0) until 1Â week after periodontal treatment (day 10). Day 4 reflects the 1Â day after periodontal treatment. B Diet analysis during the medication prescription. Statistics for blood systemic markers and diet diary are in Tables S3 and S4, respectively. Abbreviations: ESR, erythrocyte sedimentation rate; NHS, National Health Service