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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Inhibiting NLRP3 inflammasome signaling pathway promotes neurological recovery following hypoxic-ischemic brain damage by increasing p97-mediated surface GluA1-containing AMPA receptors

Fig. 3

HIBD decreases the expression of synaptic GluA1. a The expression of cytoplasmic AMPARs in the brain tissues of rats with HIBD was detected by a Western blotting. b, c The total protein levels of GluA1 (b) and GluA2 (c) in rats with HIBD remained unchanged in comparison with those in sham rats. d Western blotting was used to detect the expression of synaptic AMPARs in the brain tissues of rats with HIBD. e, f The expression of GluA1 (e), but not GluA2 (f), was notably decreased in the synaptosomal fraction in rats with HIBD compared with sham rats. The data were presented as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001

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Journal of Translational Medicine

ISSN: 1479-5876

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