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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Inhibiting NLRP3 inflammasome signaling pathway promotes neurological recovery following hypoxic-ischemic brain damage by increasing p97-mediated surface GluA1-containing AMPA receptors

Fig. 1

The NLRP3 inflammasome signaling pathway is activated in rats with HIBD. a The expression of NLRP3 inflammasome proteins in the brain tissues of rats with HIBD was detected by Western blotting. b The expression of NLRP3 showed an inverted U-shape and peaks at 6 h following HIBD. c–f The protein levels of clv-caspase-1 (d) and mature IL-1β (f), but not caspase-1 (c) and pre-IL-1β (e), were significantly increased in rats with HIBD compared with sham rats. The data were presented as the mean ± SEM. *p < 0.05, **p < 0.01

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Journal of Translational Medicine

ISSN: 1479-5876

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