The tight junction protein claudin 6 is a potential target for patient-individualized treatment in esophageal and gastric adenocarcinoma and is associated with poor prognosis

Table 4 Dysregulated gene expression in EAC and GAC cohorts

CLDN6 claudin 6, EAC esophageal adenocarcinoma, GAC gastric adenocarcinoma
^aa p-value adjusted < 0.05 was interpreted as significant (Ward test, Bonferroni correction)
^ba log2 Fold Change ≥ 1.5 was considered upregulated, a log2 Fold Change ≤—1.5 a downregulation
^cgenes exclusively up or downregulated in each tumor subgroup (CLDN6 > / < best cutoff)

ISSN: 1479-5876