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Table 3 Multivariate analysis for CLDN6 mRNA expression in EAC and GAC

From: The tight junction protein claudin 6 is a potential target for patient-individualized treatment in esophageal and gastric adenocarcinoma and is associated with poor prognosis

 

EAC

GAC

Covariate

HR (95% CI)

p-value

HR (95% CI)

p-value

Age

1.0 (0.96–1.03)

0.81

1.02 (1.0–1.04)

0.01

pT

1.17 (0.65–2.02)

0.60

1.24 (0.97–1.57)

0.08

pN

3.91 (1.32–11.64)

0.01

1.53 (1.01–2.34)

0.047

M

4.91 (1.55–15.61)

0.007

1.82 (1.0–3.32)

0.053

CLDN6 > best cutoff

0.63 (0.19–2.02)

0.44

1.50 (1.01–2.21)

0.042

  1. The bold values represent significant p-values (< 0.05)
  2. CI confidence interval, CLDN6 claudin 6, EAC esophageal adenocarcinoma, GAC gastric adenocarcinoma, HR hazard ratio, pN lymph node stage, M metastasis stage, pT Tumor stage
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Journal of Translational Medicine

ISSN: 1479-5876

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