Fig. 4

The spectrum of LCNS tumor immune environments as determined by RNA-Seq. Subtype 1 has high immune cell abundance and high immune marker expression. Subtype 2 has significantly lower immune cell levels and relatively lower immune cell marker expression. Subtype 3 has similarly low immune cell populations as the subtype 2, with the exception of macrophage levels decreased, and immune marker expression is significantly downregulated [20].