Fig. 2

Oncogenic drivers in lung cancer patients based on smoking status and ethnicity. A Distribution of oncogenic drivers in East Asian (n = 484) [24, 26, 27] and Caucasian (n = 264) [22, 28] never smoker lung cancer patients (majority with lung adenocarcinoma). B Distribution of oncogenic drivers in East Asian (n = 248) [27, 29] and Caucasian (n = 7187) [28, 30] ever smoker lung cancer patients (majority with lung adenocarcinoma). C Ratio of EGFR exon 19 deletion to exon 21 L858R substitution between East Asian ever smokers (n = 39) [31], East Asian never smokers (Taiwanese, n = 65) [21], and Caucasian never smokers (n = 39) [20]. NS never smoker; ES ever smoker