Skip to main content
Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Suppressive stroma-immune prognostic signature impedes immunotherapy in ovarian cancer and can be reversed by PDGFRB inhibitors

Fig. 4

The tumor microenvironmental landscape between the high and low SIPS patients. The boxplot showed the levels of SIPS score of patients with different immune subtypes including A MFP and B TCGA subtypes in TCGA-OV cohort. C The boxplots showed the tumor microenvironmental components estimated by xCell algorithm in TCGA-OV cohort. D The heatmap showed the expression levels of several immune-related key genes in patients with different SIPS subtypes in Affy cohort. E The radar plot showed the correlation between SIPS and the tracking tumor immunophenotype in TCGA-OV cohort. F The ridge plot showed the enriched GO biological progress of the 150 hub genes derived from the WGCNA-STRING-Cytoscape analysis. G The UMAP plot showed a total of 51,786 cells in tumor microenvironment, and cell clusters were color-coded and labeled according to the original definition in the GSE165897 dataset. H The dot plot showed the levels of the 15 immune-related signatures derived from SIPS in the tumor microenvironment components

Back to article page