Fig. 5

HBOT modulates mitochondrial stress after sciatic nerve injury. A The transcription level of mitochondria protein TSPO in the sciatic nerve-DRG after 12 days of nerve injury. B The transcription level of mitochondria protein TSPO in the spinal cord after 12 days of nerve injury. C Double immunofluorescence of TRPV1 (Green) and TSPO (Red), Co-localization of TRPV1 and TSPO (Orange) in the DRG after 12 days of nerve crush. scale bar: 100 µm. D The number of cells that were IR-positive for TSPO in the DRG. E The percentage of cells that were IR-positive for both TRPV1 and TSPO in the DRG. F Representative images of TSPO in the spinal cord of the naïve, SNC and SNC^(HBOT) group after 12 days of nerve injury. scale bar: 100 µm. The number of cells that were IR-positive for TSPO in the spinal cord. RT-PCR (4–7), IHC (n = 4–6 animals). One-way Anova-Followed with Tukey’s test. Mean ± SEM. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001