Fig. 2

Sciatic nerve injury promotes neuroinflammation in the DRG and spinal cord. A Gene-expression related to inflammation in the sciatic nerve and DRG after 12 days of the sciatic nerve crush. B Gene-expression related to inflammation in the lumbar spine after 12 days of the sciatic nerve crush. C Positively stained cells with IBA1 (Red) and merged with dapi stain (blue) in the DRG and spinal cord in the naïve, SNC and SNC^(HBOT) group. Scale bar: 100 µm. D The number of positively stained cells with IBA1 in the DRG E The number of positively stained cells with IBA1 in the spinal cord. F Positively stained cells with MMP-9 (Green) and merged with dapi stain (blue) in the spinal cord in the naïve, SNC and SNC^(HBOT) group. Scale bar: 100 µm. G The number of positively stained cells with MMP-9 in the spinal cord. RT-PCR (n = 4–7), IHC (n = 4–6 animals). One-way Anova-Followed with Tukey’s test. Mean ± SEM. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001