Table 1 Protocol of primary study

• Baseline questionnaires

• 26 weekly web diaries for symptom and stress ratings, activity patterns, hassles and uplifts

• 26 weekly collections of heart monitor data (autonomic activity)

• Initial 13 weeks of waking actigraphy data collection

• Six-month follow-up interviews for functional assessment and global change ratings

• Data analysis of biobehavioral predictors of subjects classified into “improved” and “non-improved” groups