Fig. 4

LAD1 enhances cell invasion and migration in vivo and in vitro. A, B Wound healing ability when transfected with ShLAD1 and LAD1. C, D Invasion and migration ability when transfected with ShLAD1 and LAD1. E Xenograft tumor clustering and overall state in MKN45 cells after LAD1 knockdown (n = 5 in every group). F Tumor volume growth curve in three groups. G Tumor weight of xenografts in the three groups. H Lung metastasis in MKN45 cells with LAD1 knockdown. I Lung metastasis count in the three groups. Significance as above