Fig. 2

JorA represses xenografted bladder tumors growth in vivo. A Diagram of xenograft experiment. B Curves of the xenografted tumor volume in two groups of mice. The statistical difference was analyzed by one-way ANOVA, *p < 0.05. C The photos of mice body (with subcutaneous tumors). D Tumor weight of mice in both groups. P-values were derived from Two-tailed Student’s t-test, **p < 0.01. E Body weight of mice in both groups. F H&E staining photos of xenografted tumor sections. The arrows indicate the vascular section in the slice. G IF staining for vascular marker CD31 xenografted tumor sections. The arrows indicate the vascular section in the slice. H Quantitative contrast map of abundant blood vessels in xenografted tumor. The ordinate represents the relative abundance of blood vessels (take control group as 100%). P-values were derived from Two-tailed Student’s t-test, *p < 0.05. I Immunohistochemical staining results of Ki67 in xenografted tumor sections. J Quantitative contrast map of Ki67. The ordinate represents the proportion of Ki67 positive cells. P-values were derived from Two-tailed Student’s t-test, *p < 0.05. K IF staining results of Ki67 in xenografted tumor sections. L H&E staining photos of mice liver sections. M H&E staining photos of mice kidney sections