Fig. 5

Effects of NAG treatment on histological alterations and the remyelination of musculocutaneous nerves. A Histological images of LFB-stained musculocutaneous nerve sections in the groups. Scale bar represents 20 μm. B Average ratio of the diameter of musculocutaneous nerves of the right (injury) to the left (intact) side at 8 weeks postsurgery. C Average ratio of the number of LFB-positive axons of the right (injury) to the left (intact) side at 8 weeks postsurgery. D–J The mRNA levels of myelination-associated genes (egr2, GAP-43, hmgcr, L1CAM, mpz, pmp22, and prx) were determined using qRT‒PCR. K–N The mRNA levels of demyelination-associated genes (ngfr, notch1, pou3f1, and sox2) were determined using qRT‒PCR. The data shown are the mean ± SD in each group; ***P < 0.001, **P < 0.01, *P < 0.05. NS normal saline, NAG acetylglutamine