Fig. 5
From: Fibrosis and bone marrow: understanding causation and pathobiology
Primary myelofibrosis with osteomyelosclerosis: A sclerotic marrow, increased vascularity and woven bone (H&E, × 100) B markedly sclerotic marrow with prominent focal proliferation of abnormal megakaryocytes, high vascularity and dilated vascular channels (H&E, × 200). C diffusely increased, dense reticulin network with many intersections; trapped megakaryocytes (Gomori reticulin, × 200) D diffusely increased collagen, particularly surrounding foci of abnormal megakaryocytic proliferation (Masson trichrome, × 200)