Fig. 1

The expressions and correlations of COX-2 and Caspases-1 in platelets of ITP patients and healthy controls. A The mRNA levels of COX-2 in platelets. B Representative western blot of Caspase-3, Caspase-3 p17 subunit, Caspase-1 and COX-2. C Relative protein expression of COX-2 (left) and Caspase-1 (right). Values were calculated as the ratio of the gray values of the target proteins to GAPDH. D Correlation of platelet count and mRNA level of COX-2. E The correlations of platelet count with the protein expressions of COX-2. F The correlations of the expression of COX-2 protein levels with Caspase-1. HC: healthy control, ITP: immune thrombocytopenia, Plts: platelet count