Fig. 3From: Spatial tumour gene signature discriminates neoplastic from non-neoplastic compartments in colon cancer: unravelling predictive biomarkers for relapseExamples of spatial distributions of 5 out of 176 genes in neoplastic and non-neoplastic tissue. a The virtually stained H&E images of the samples from non-relapsed (patient 1–5) and relapsed patients (patient 6–10). b Expression and the spatial distribution of MET, a gene of the tumour gene signature that was used for the creation of the neoplastic tissue compartment. c Exemplified expression and the spatial distribution of MUC2, a gene expressed in non-neoplastic epithelial- and cancer cells. d Exemplified expression and the spatial distribution FABP1, a high expressed gene in colonic tissue. e Expression of OLFM4, a gene associated to inflamed colonic epithelium and antiapoptotic features. f Expression of COL1A, a gene relevant in forming collagen and found in most connective tissues. Total counts of each transcript are depicted in each image and size bar is the same for all imagesBack to article page