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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation

Fig. 6

The SGK1 and PI3Kγ pathways were activated in the LIGHT-stimulated heart. a Volcano plot of 661 differentially expressed genes. b GO and KEGG enrichment analyses of 661 differentially expressed genes. c Western blot images of SGK1, AKT, phospho-AKT, and PI3Kα/γ, and d relative expression in the heart samples normalized to the control. *p < 0.05, **p < 0.01. SGK1: serum and glucocorticoid-inducible kinase 1; AKT: protein kinase B; PI3Kα/γ: phosphoinositide-3 kinase α/γ

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