Fig. 5

LIGHT contributes to myocardial fibrosis. a Typical histological images of the mouse ventricular and b atrial tissues from both groups stained with H&E and Masson. c Quantification of cardiac fibrosis of ventricular and atrial in the different groups. d, e Western blot images of collagen I, collagen III, α-SMA, Smad2/3, and phospho-Smad2/3, and f relative expression in the heart samples normalized to the control. *p < 0.05, **p < 0.01. α-SMA: α-smooth muscle actin