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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation

Fig. 3

LIGHT contributes to cardiac dysfunction and AF. a Representative images of cardiac morphology with or without LIGHT treatment. b Typical echocardiography of the heart with or without LIGHT treatment. cj Ratio of heart weight/body weight, heart weight/tibia length, NT-proBNP, LVEF, LVFS, LVIDd, and LAD and AF inducibility in the control and LIGHT (+) groups. (k) Representative images of surface and RA EGM in the LIGHT (−) and LIGHT (+) groups. *p < 0.05, **p < 0.01. RA: Right atria; EGM: Electrogram, NT-proBNP: N-terminal pro brain natriuretic peptide

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