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Fig. 10 | Journal of Translational Medicine

Fig. 10

From: Low-intensity pulsed ultrasound ameliorates glia-mediated inflammation and neuronal damage in experimental intracerebral hemorrhage conditions

Fig. 10

Schematic diagram of LIPUS-improved ICH outcomes and microglial and astrocyte expression. Following ICH, erythrocytes accumulate around damaged cerebral vessels, and thrombin not only aids in blood coagulation but also activates microglia and astrocytes. LIPUS treatment regulates the PI3K/Akt-NF-κB signaling pathways, reducing microglia-induced neurotoxicity and inhibiting astrocytic neurotoxicity, which contributes to the amelioration of ICH outcomes. LIPUS intervention after ICH also promotes anti-inflammatory effects and decreases apoptosis

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Journal of Translational Medicine

ISSN: 1479-5876

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