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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Discovery of therapeutic targets for spinal cord injury based on molecular mechanisms of axon regeneration after conditioning lesion

Fig. 5

Drug prediction of hub genes. A Heatmap of hub genes with degree score ≥ 30, 9 hub genes marked with asterisks were identified by the GSE96051 dataset verified; B qRT-PCR showing the expression levels of hub genes (Sham and SNI groups, unpaired t-test, n = 6 mice/group). C In the drug-hub gene network, blue indicates hub genes and green indicates predicted drugs. (“Young vs NC”: young, 2-month-old mice, injury group vs the normal control group GSE58982; “Old vs NC”:24-month-old mice, injury group vs the normal control group in GSE58982; “Injury vs NC”: injury group vs the normal control group in GSE96051). *P < 0.05, **P < 0.01, ***P < 0.001

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