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Table 5 Anti-HFG mAb epitope expression in human cancer cell lines

From: Novel heavily fucosylated glycans as a promising therapeutic target in colorectal cancer

Type

Cell line

anti-HFG mAb binding

Gastric cancer

AGS

 +  +  + 

 

TSGH9201

 + 

 

NCI-N87

 +  + 

 

KATO III

−

 

MKN45

−

 

MKN74

−

 

MKN7

−

Colon cancer

LOVO

−

 

COLO 205

−

 

COLO 201

 + 

 

SW1116

 +  +  + 

 

DLD-1

 +  + 

 

LS 174 T

 + 

 

HT-29

−

 

T84

−

Breast cancer

MCF-7

 +  + 

 

MDA-MB-231

−

 

MDA-MB-453

−

 

T-47D

−

Ovarian cancer

NIH: OVCAR-3

 + 

 

SW626

 + 

 

SK-OV-3

−

 

ES-2

−

Pancreatic cancer

SU.86.86

−

 

EBC-1

−

 

PANC-1

−

Lung cancer

NCl-H146

 + 

 

NCl-H209

−

Skin cancer

A431

−