Fig. 11

Visualization of molecular docking simulation of resveratrol towards IL11. A Docking models for resveratrol-IL11. Resveratrol and IL11 subunit are illustrated in stick-form and as cartoons respectively. B 2D molecular interactions are illustrated for resveratrol-IL11. The pyrazole nitrogen of resveratrol forms a hydrogen bond with ASP134 of IL11. The interactions involving hydrogen bonds are depicted through green dashed lines, while van der Waals interactions are represented by light green dashed lines. The alkyl interaction is denoted by a pink dashed line. The docking analyses were performed using BIOVIA Discovery Studio, with details provided in the Methods Sect. 3D molecular interactions are illustrated for C hydrogen bonds between resveratrol and IL11 within the binding site, and D hydrophobicity surface view at the interface between resveratrol and IL11, respectively. The depiction of resveratrol's molecular structure is rendered in bold stick form, with potential binding sites being indicated by light stick forms