Fig. 2

GAA suppresses the malignant phenotypes of OC cells in vitro and in vivo. A Wound healing assay of A2780 cells treated with GAA for 0 h, 24 and 48 h. B Cell spheroidization assay of A2780 cells treated with GAA. C Clonogenic assays of A2780 cells treated with GAA for 48 h. D Flow cytometry analysis showing cell cycle changes in A2780 cells treated with GAA for 48 h. E–G Image showing tumor inhibition by GAA, with measurements of tumor weight and volume. H–K Graphs showing changes in serum levels of BUN, AST, CRE, and ALT in the mouse model. L IHC results of the staining patterns of Ki-67, CDK4, and CDK6 proteins in tumors