Fig. 1From: An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathwayHippocampal Fgr was increased in the CLP mouse model. A The mRNA levels of Src family kinase members in the hippocampus after CLP surgery (n = 3 for control mice; n = 4 for CLP mice; mean ± SEM, unpaired t-test, *p < 0.05). B Level of Fgr protein in the hippocampus of septic mice (n = 3, mean ± SEM, unpaired t-test, *p < 0.05). C, D Representative fluorescent images (C) and quantitative analysis (D) of Fgr in hippocampal neurons from septic mice (n = 3, mean ± SEM, unpaired t-test, ***p < 0.001). E Fgr was not co-localized with GFAP and Iba1 in the hippocampus of septic mice. Scale bar, 50 μmBack to article page