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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Attenuated Dengue virus PV001-DV induces oncolytic tumor cell death and potent immune responses

Fig. 4

Supernatant from PBMCs cultured with Dengue virus increases surface receptors for Dengue virus cell binding and entry as well as immune checkpoint inhibition on tumor cells. A Flow plot analysis of MDA-MB-231 tumor cells by flow cytometry for expression of Dengue virus receptor ligands, DC-SIGN and Syndecan-1, as well as immune checkpoint receptor, PD-L1. B Fold change of receptors comparing levels from the PV001-DV supernatant treatment (DV sup) over media control (Control sup)

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