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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Altered insulin secretion dynamics relate to oxidative stress and inflammasome activation in children with obesity and insulin resistance

Fig. 5

Inflammatory markers of the study population. Total leukocyte count A, total neutrophil count B, total lymphocyte count C, total monocyte count D, total platelet count E, systemic immune-inflammation index F, systemic inflammation response index G, aggregate index of systemic inflammation H, monocyte to lymphocyte ratio I, neutrophil to lymphocyte ratio J, plasmatic C-reactive protein K, plasmatic ferritin L, plasmatic creatinine M, and plasmatic uric acid N. White bars with dots represent lean children (n = 30), grey bars represent metabolically healthy children with obesity (n = 35), white bars represent the early responder group (n = 19), and black bars represent the late responder group (n = 32). Values are means ± SEM. P < 0.05 was considered for statistical significance. (*) shows significant differences relative to lean children, a shows significant differences relative to EP-OBIR + children, b shows significant differences relative to OBIR- children, and (#) shows significant differences along the OGTT. ObIR-, non-insulin resistant children with obesity; ObIR + , insulin resistant children with obesity; EP-OBIR + , early peak OBIR + children; LP-OBIR + , late peak OBIR + children; SII, systemic immune-inflammation index; SIRI, systemic inflammation response index; AISI, aggregate index of systemic inflammation; MLR, monocyte to lymphocyte ratio; NLR, neutrophil to lymphocyte ratio; A.U., arbitrary units; CRP, C-Reactive Protein

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