Fig. 3

Antioxidant system-related enzyme activities in erythrocytes in the study population. TAC A, GR B, G6PDH C, and 6PGDH D activities were measured at baseline and along the OGTT. White bars with dots represent lean children (n = 20), grey bars represent OBIR- children (n = 13), white bars represent EP-OBIR + children (n = 10), and black bars represent LP-OBIR + children (n = 25). Values are means ± SEM. P < 0.05 was considered for statistical significance. (*) shows significant differences relative to lean children, a shows significant differences relative to EP-OBIR + children, b shows significant differences relative to OBIR- children, and (#) shows significant differences along the OGTT. ObIR-, non-insulin resistant children with obesity; ObIR + , insulin resistant children with obesity; EP-OBIR + , early peak OBIR + children; LP-OBIR + , late peak OBIR + children; NADP, nicotinamide-adenine dinucleotide phosphate; TAC, total antioxidant capacity; GR, glutathione reductase; G6PDH, glucose-6-phosphate dehydrogenase; 6PGDH, 6-phosphogluconate dehydrogenase; OGTT, oral glucose tolerance test