Fig. 2

Levels of oxidative damage present in erythrocytes and plasma of the study population. TBARS levels were measured in erythrocytes A and plasma D at baseline and along OGTT, and carbonyl group levels were measured at baseline in erythrocytes B and plasma E. Also, erythroid osmotic fragility C was quantified in every group. White bars with dots represent lean children (n = 17), grey bars represent OBIR- children (n = 13), white bars represent EP-OBIR + children (n = 13), and black bars represent LP-OBIR + children (n = 17). Values are means ± SEM. P < 0.05 was considered for statistical significance. (#) shows significant differences relative to 90 mM of NaCl, (*) shows significant differences relative to lean children, a shows significant differences relative to EP-OBIR + children, and b shows significant differences relative to OBIR- children. ObIR-, non-insulin resistant children with obesity; ObIR + , insulin resistant children with obesity; EP-OBIR + , early peak OBIR + children; LP-OBIR + , late peak OBIR + children; OGTT, oral glucose tolerance test; MDA, malondialdehyde; TBARS, thiobarbituric acid reacting substances; C = O, carbonyl groups