Fig. 8

MAFK serves as a biomarker in LUAD. GSVA score of MAFK regulon between low- and high-risk subgroups (A) or clinical stages (B) in the TCGA-LUAD dataset. C RT-qPCR detection of MAFK expression in normal BEAS-2B cell line and lung cancer cell lines. D Western blot detection of MAFK expression in normal NP69 cell line and lung cancer cell lines. E Western blot detection of MAFK expression in patients’ cancerous tissue and adjacent normal tissue. F DepMap score of MAFK in different lung cancer cell lines. G GO enrichment analysis of genes in MAFK regulon. H–K Visualization of the docking results of proteins encoded by prognostic genes with small molecular compounds. L Summary of this study. ‘ns’ means no statistical significance, ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001 and ∗∗∗∗P < 0.0001