Fig. 5

Characterization of genome alterations in LPRI subgroups. A Oncoprint shows the differentially altered gene mutations or CNV regions between high and low-risk subgroups. B Difference in mutational signatures between high and low-risk subgroups. C–E Comparisons of the stemness, loss of heterozygosity, genome alterations, and instability between low- and high-risk subgroups. ‘ns’ means no statistical significance, ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001 and ∗∗∗∗P < 0.0001