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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: DNMT3A mutation promotes leukemia development through NAM-NAD metabolic reprogramming

Fig. 6

Intervention of NAMPT prolongs the survival of tumor-bearing mice and reduces splenic infiltration. A Schematic diagram of the animal experiment. B, C Tumor fluorescence imaging and mean photon counts of three groups of mice after treatment or non-treatment for 20 days. D Kaplan–Meier survival curve of the three groups of mice. E Splenic infiltration of tumors of the three groups of mice. F The statistical diagram depicts the length of the longitudinal axis of the spleen in the indicated three groups of mice (n = 5 for each group). *p ≤ 0.05, **p ≤ 0.01 (Student’s T-test)

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