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Table 3 Factors influencing gestational diabetes based on a univariate logistic regression model

From: Remnant cholesterol, but not other cholesterol parameters, is associated with gestational diabetes mellitus in pregnant women: a prospective cohort study

 

Non-GDM (n = 553)

GDM (n = 37)

OR (95%CI)

P-valve

Age (years)

32.03 ± 3.81

32.54 ± 3.56

1.036 (0.949, 1.132)

0.43038

Nulliparity (n,%)

 No

291 (52.62%)

19 (51.35%)

Ref

 

 Yes

262 (47.38%)

18 (48.65%)

1.052 (0.541, 2.048)

0.881

Pre-pregnancy BMI (kg/m2)

21.78 ± 3.20

25.95 ± 5.17

1.284 (1.183, 1.392)

 < 0.001

GGT (IU/L)

13.72 ± 8.38

18.81 ± 10.97

1.040 (1.014, 1.066)

0.002

TC (mg/dL)

172.32 ± 26.97

180.89 ± 29.61

1.011 (0.999, 1.023)

0.065

TG (mg/dL)

115.16 ± 41.67

176.22 ± 81.93

1.019 (1.012, 1.025)

 < 0.001

HDL-c (mg/dL)

65.29 ± 13.25

59.29 ± 16.45

0.966 (0.941, 0.992)

0.009

LDL-c (mg/dL)

84.01 ± 21.29

84.29 ± 28.38

1.001 (0.985, 1.016)

0.939

HLR

0.84 ± 0.31

0.81 ± 0.40

0.733 (0.240, 2.245)

0.587

RC (mg/dL)

23.03 ± 8.34

37.31 ± 18.63

1.102 (1.067, 1.138)

 < 0.001

Hepatic steatosis (n, %)

 Grade 0

463 (83.73%)

16 (43.24%)

Ref

 

 Grade 1

76 (13.74%)

9 (24.32%)

3.427 (1.462, 8.033)

0.005

 Grade 2

9 (1.63%)

9 (24.32%)

28.937 (10.128, 82.677)

 < 0.001

 Grade 3

5 (0.90%)

3 (8.11%)

17.362 (3.814, 79.042)

 < 0.001

Adipokines (ng/mL)

6289.62 ± 4296.63

2591.20 ± 2133.90

0.999 (0.999, 1.000)

 < 0.001

AST (U/L)

17.71 ± 8.14

19.89 ± 7.34

1.020 (0.994, 1.047)

0.140

ALT (U/L)

11.00 (8.00–14.00)

15.00 (10.00–25.00)

1.037 (1.014, 1.061)

0.002

FPG (mg/dL)

76.54 ± 9.06

84.85 ± 15.10

1.072 (1.039, 1.106)

 < 0.001

Insulin (μIU/mL)

8.10 (5.30–11.20)

15.30 (9.10–22.50)

1.123 (1.073, 1.175)

 < 0.001

HOMA-IR

1.50 (1.00–2.20)

2.90 (1.60–4.60)

1.463 (1.211, 1.766)

 < 0.001

  1. Continuous variables were summarized as mean (SD) or medians (quartile interval); categorical variables were displayed as a percentage (%)
  2. RC remnant cholesterol, BMI body mass index, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT gamma-glutamyl transferase, HDL-c high-density lipoprotein cholesterol, TC total cholesterol, TG triglycerides, LDL-c low-density lipid cholesterol, HLR high-density lipoprotein cholesterol to low-density lipid cholesterol ratio, FPG fasting plasma glucose, HOMA-IR homeostasis model assessment-insulin resistance
  3. OR odds ratio, CI confidence interval, Ref Reference