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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Activation of CTNNB1 by deubiquitinase UCHL3-mediated stabilization facilitates bladder cancer progression

Fig. 7

Amplification of UCHL3 was associated with worse prognosis. A The GEPIA database was employed to analyze UCHL3 expression in BLCA and normal tissues. B The Sanchez-Carbayo Bladder 2 database was employed to analyze UCHL3 expression in patients with no value, infiltrating bladder urothelial carcinoma, and superficial bladder cancer. C The Dyrskjot Bladder 3 database was employed to analyze UCHL3 expression in patients with no value, infiltrating bladder urothelial carcinoma and superficial bladder cancer. D Immunohistochemical analysis of UCHL3 was undertaken with a tissue microarray of human bladder cancer samples. Bar = 100 µm. E Quantitative histoscore of immunohistochemical staining for UCHL3. F The impact of UCHL3 on the overall survival of bladder cancer was evaluated via the GSE31684 dataset. G The GEPIA database was adopted to analyze the difference in disease-free survival among bladder cancer patients based on UCHL3 expression. H Western blots analyzing UCHL3 expression in several bladder cancer tissues

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