Association between Chinese visceral adiposity index and risk of stroke incidence in middle-aged and elderly Chinese population: evidence from a large national cohort study

Table 3 The association of CVAI with stroke in different blood pressure status

CVAI	Total N	No. of events (incident rate^a)	Model 1		Model 2		Model 3
CVAI	Total N	No. of events (incident rate^a)	h (95% CI)	P value	HR (95% CI)	P value	HR (95% CI)	P value
Normotension
CVAI^b	2421	99 (5.87)	1.27 (1.02–1.59)	0.032	1.28 (1.02–1.60)	0.035	1.32 (1.03–1.69)	0.030
Q1	910	23 (3.62)	Ref.
Q2	720	36 (7.18)	1.91 (1.13–3.22)	0.015	1.93 (1.14–3.27)	0.014	1.83 (1.07–3.11)	0.027
Q3	516	25 (6.95)	1.87 (1.06–3.30)	0.030	1.92 (1.08–3.42)	0.026	1.95 (1.09–3.50)	0.025
Q4	275	15 (7.90)	2.11 (1.10–4.04)	0.025	2.11 (1.08–4.10)	0.028	2.18 (1.07–4.42)	0.032
Prehypertension
CVAI^b	1934	124 (9.25)	1.42 (1.18–1.69)	< 0.001	1.44 (1.21–1.72)	< 0.001	1.45 (1.20–1.76)	< 0.001
Q1	502	22 (6.31)	Ref.		Ref.		Ref.
Q2	501	26 (7.45)	1.19 (0.67–2.09)	0.557	1.25 (0.71–2.22)	0.445	1.31 (0.73–2.35)	0.372
Q3	518	37 (10.33)	1.66 (0.98–2.81)	0.061	1.84 (1.07–3.17)	0.027	1.77 (1.01–3.12)	0.047
Q4	413	39 (13.71)	2.21 (1.31–3.73)	0.003	2.38 (1.39–4.07)	0.002	2.46 (1.38–4.38)	0.002
Hypertension
CVAI^b	2887	389 (19.68)	1.19 (1.08–1.32)	0.001	1.16 (1.04–1.29)	0.006	1.05 (0.93–1.18)	0.442
Q1	398	35 (12.83)	Ref.		Ref.		Ref.
Q2	590	70 (17.40)	1.27 (0.85–1.90)	0.251	1.34 (0.89–2.03)	0.164	1.32 (0.87–2.03)	0.196
Q3	777	102 (19.10)	1.40 (0.96–2.06)	0.084	1.44 (0.97–2.14)	0.070	1.38 (0.92–2.08)	0.125
Q4	1122	182 (23.72)	1.72 (1.20–2.47)	0.003	1.66 (1.14–2.42)	0.008	1.34 (0.90–2.01)	0.150

Model 1: unadjusted
Model 2: adjusted for sex, SBP, DBP, rural residence, smoking, and alcohol consumption status
Model 3: model 2 + further adjusted for region, marital status, education, heart rate, FBG, serum creatinine, TC, LDL, dyslipidemia, heart disease, kidney disease, and DM
CI confidence interval, DBP diastolic blood pressure, DM diabetes mellitus, FBG fasting blood glucose, HR hazard ratio, LDL low density lipoprotein, Q quartile, Ref reference, SD standard deviation, SBP systolic blood pressure, TC total cholesterol
^aIncident rate was presented as per 1000 person-years of follow-up
^bPer SD increase

ISSN: 1479-5876