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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Targeting RNA-binding protein HuR to inhibit the progression of renal tubular fibrosis

Fig. 3

Treatment with KH3 ameliorates mouse renal atrophy and IR-induced tubular injury and fibrosis. a–c kidney weight (a), mRNA expression of tubular injury markers, NGAL (b) and KIM-1 (c) (n = 5/group). d Representative microscopic images showing PAS staining and Masson’s Trichrome staining of the kidney sections used to detect tubular injury, inflammation and collagen deposition (stained blue). Magnification, ×200. e–f The graphs summarized the results of tubular injury (e) and collagen deposition (f) quantified by image-J. *P < 0.05 vs untreated mice or contralateral kidney (CTL). #P < 0.05 vs untreated IR-injured kidney (IR)

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