Fig. 11
From: Targeting RNA-binding protein HuR to inhibit the progression of renal tubular fibrosis
Treatment with KH3 inhibits TGFß1-induced cellular generation of TGFß1, PAI-1 and Nox4 in cultured HK2 cells. a, b mRNA expression of TGFß1 (a) and PAI-1 (b) in cultured HK2 cells. c Representative Western blots illustrating PAI-1, Nox4 and GAPDH protein expression in untreated or treated HK2 cells. d, e The graphs summarize the results of band density measurements for PAI-1 (e) and Nox4 (e), respectively. The protein values are expressed relative to untreated cells, which was set at unity. *P < 0.05, vs. untreated cells; #P < 0.05, vs. TGFß1 alone treated cells