Fig. 1
From: Targeting RNA-binding protein HuR to inhibit the progression of renal tubular fibrosis
Renal tubulointerstitial HuR expression was elevated in progressive CKD patients. a, b. Representative microphotographs stained for PAS (a) from kidney biopsy tissue of patients with progressive IgA nephropathy (IgAN, n = 3), or diabetic nephropathy (DN, n = 3), or lupus nephritis (LN, n = 3), or focal segmental glomerulosclerosis (FSGS, n = 3), or thrombotic microangiopathy (TMA, n = 3) (×400 magnification) and their immunofluorescent stained for HuR (red) and DAPI (blue) (b), compared with normal kidneys (NC, n = 3). Tubular cytoplasm staining for HuR was clearly seen in the enlarged photos. Scale bars for HuR staining photos represent 50 µm. c Relative integrated pixel density of the staining of HuR specially in renal tubulointerstitial area, as quantified by image-J. *P < 0.05 vs. normal kidney (NC)