Fig. 8
From: The promoting effect and mechanism of Nrf2 on cell metastasis in cervical cancer
Snail1 plays an important role in the resistance to anoikis caused by Nrf2 in cervical cancer cells. A Measuring the levels of EMT-associated proteins, including N-cad, E-cad, Snail1, Slug, Smad and Vimentin, under ATT and SUS conditions. C The expression of FAK, pro-Caspase-3 and pro-PARP1 when Snail1 was overexpressed in the SUS state. E Overexpressing Snail1 in Nrf2 knockout HeLa cells and testing the levels of FAK, pro-Caspase-3 and pro-PARP1 under different conditions. G Snail1 siRNA was used to treat HeLa sg-Nrf2 cells, and the expression of FAK, pro-Caspase-3 and pro-PARP1 was measured. B, D, F, H The protein expression levels were quantitatively analyzed. * P < 0.05, ** P < 0.01 (n = 3)